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The phrase 'despite compromising' is correct and usable in written English.
You can use it when you want to explain that someone or something has done something contrary to their own interests or beliefs, in spite of giving up something in return. For example: "Despite compromising his ideals for a promotion, John was still not satisfied with his new job."
Exact(1)
Despite compromising with Sanders delegates on the platform, it's looking like Hillary intends to ignore the more progressive platform planks and govern from the corporate center.
Similar(59)
The spokesman acknowledged that despite years of compromising U.S. government computers, the hackers had obtained little of value, especially on the hard drives of congressional offices.
His drinking and her eagerness to get in on the act (despite iffy pipes) are compromising a regular gig on a radio show.
Despite the playwright's distancing devices, we should never feel too far from the funky smell these women emit as they try to make it in a compromised world without compromising their romantic dream of life with their children in the glow of a better day.
Teams make human errors despite technical expertise and knowledge, compromising patient safety.
In this last case, the brittle fracture of the oxides becomes dominant despite of the interlocking effect, by compromising the resistance in the plastically deformed region of the aluminium button in which the corrosive attack induces the formation of circular cracks on the bottom rivet leading to rupture the joint.
However phrased, it is indeed compulsive drug use that is widely seen as a core aspect of addiction, and by that is meant repeated, persistent use, despite placing an individual in danger, compromising their health, family and social lives.
Actually, this dose-intensified biweekly administration seems to be more effective at increasing response rate and progression-free survival than conventional dose and schedule of capecitabine in colon cancer, without compromising its safety profile, despite the fact that capecitabine was administered with oxaliplatin (Thomas et al, 2001; Scheithauer et al, 2002, 2003).
In summary, the results suggest the combined intervention improved some aspects of writing, without compromising the improvement of WM, despite the lesser intensity of specific training compared with the intervention only in WM (12 vs. 23 sessions), and reduced the severity of hyperactivity symptoms.
Our policy is to reserve corticosteroid treatment to patients with significant cerebral edema with mass effect, compromising mental or neurological status, despite maximal surgical treatment.
Compromising for what reason?... What is compromise?" .
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com