"despite all these difficulties" is correct and usable in written English.
You can use it to express that something has happened in spite of the many challenges something faced. For example: "Despite all these difficulties, we were able to complete the project on time."
Despite all these difficulties, the consolidation method has been successfully applied.
Despite all these difficulties, the Bethlehem exile resettlement has been cited by some E.U. leaders as a precedent for resettling the 60 or so Guantánamo detainees that the Obama administration is hoping to turn over to Europe.
Tony Abbott, the Australian Prime Minister said that despite all these difficulties, those leading the effort remain undaunted and officials are "well, well short" of any point where they would scale back the hunt.
Moreover, there are uncomfortable contradictions between individual human rights and the kind of group rights often represented by such claims.And yet Mr Barkan makes a persuasive case that, despite all these difficulties, the recent vogue for apologies and restitution should be welcomed.
Despite all these difficulties, art investment is a big business.
Despite all these difficulties, some rural students still excel in their academic performance.
Libraries have no mandate to collect apps, such as Angry Birds or Instagram, which form part of popular culture.Despite all these difficulties, the world's libraries have tried for over a decade to conserve some aspects of their national digital heritage.
"Despite all those difficulties and setbacks, we've moved forward substantially and should finish the project by March".
I remember the troubles that John Major had navigating debates over Europe, and that one of his achievements, despite all those difficulties, was securing the location of the European Medicines Agency EMAA) in the UK.
Despite all those difficulties, there are surely people who will not be satisfied unless Zimmerman is convicted and sentenced to the maximum penalty allowed by law in this case, life in prison.
Despite all those difficulties, there are surely people who will not be satisfied unless Zimmerman is convicted and sentenced to the maximum penalty allowed by law — in this case, life in prison.
