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Despite advanced knowledge of the autophagy lysosomal regulation during stress, the precise mechanism by which this pathway responds to oncogenic signaling remains unclear.
Despite advanced facilities and sophisticated control algorithm which are available in engineering practice, heating, ventilating and air conditioning system (HVAC) constantly works not properly in many buildings.
Despite advanced engineering design, sophisticated manufacturing techniques, and extensive bench, pre-clinical, and clinical testing, lead failure (LF) remains the Achilles' heel of the ICD system.
Despite advanced optimizations applied across various layers along the odyssey of data access, the I/O stack still remains volatile.
Despite advanced optimizations applied across various layers along the odyssey of data access, the Linux I/O stack still remains volatile.
Despite advanced, aggressive ICU management of the septic patient, lethality rates remain at 40-60% for patients in septic shock [26].
Despite advanced stabilization technology, shaking does happen.
Despite advanced PAH therapies, the 3-year survival of SSc-associated PAH (SSc-PAH) is around 50% [ 1].
21, 22, 42– 44 Some patients show long-term survival despite advanced melanoma having the reputation of being associated with a particularly dismal prognosis.
Despite advanced, aggressive ICU management of the septic patient, lethality rates remain at 40-60% for patients in septic shock [ 26].
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