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Discover LudwigThe phrase "despair and" is a perfectly acceptable phrase to use in written English.
For example, "The family had been living in poverty and despair and needed help to make ends meet."
Exact(60)
Despair and death follow.
to despair and utter hopelessness.
PARKS: Gloom, despair and tragedy.
That's unknowable: despair and passivity may triumph.
Throughout, Ms. Chen balances despair and humor.
Despair and rapture on the same page.
"I despair and I do not understand".
Timbuktu teeters between despair and hope.
We despair, and take on pained faces.
Despair and hope all in one day.
They skid downhill into despair and delusions.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com