Sentence examples for desired specificity from inspiring English sources

Phage display is an alternative method for constructing and selecting antibodies with desired specificity towards an antigen.

Chimeric antigen receptors (CARs) are artificially engineered receptors that confer a desired specificity to immune effector T cells.

The suitability of a technique is determined by the availability of funds, required accuracy, structure and composition of vegetation, and desired specificity of estimation (Catchpole and Wheeler 1992).

An understanding of the structure and function of serpins has suggested that they may provide novel scaffolds for engineering protease inhibitors of desired specificity for therapeutic use.

A preferred approach to endow effector T cells (Teff) with a desired specificity uses chimeric immune receptors with antibody-type specificity.

In addition, the proposed methodology is customizable thanks to the use of two thresholds allowing the user to define the desired specificity level in the display.

Antibodies have been the paradigm of binding proteins with desired specificities for more than one century and during the past decade their recombinant or humanized versions have entered clinical application with remarkable success.

Here, the notion that "instant vaccines" can be created and delivered using principles of synthetic biology, advances in immunology, and genetic engineering to generate human T cells that display desired specificities and enhanced functionalities is reviewed.

In conjunction with the isolation of sdAbs with the desired specificities from non-immune phage display libraries, the decabody strategy provides a means of generating high avidity bispecific antibody reagents, with good physical properties, relatively quickly.

To fully exploit these advances, novel techniques were needed to screen the massive V-domain libraries for desired specificities.

It allows the isolation of a large repertoire of human mAbs with desired specificities to be selected from a small (~8 ml) volume of peripheral blood, and can be used with either fresh or frozen B-lymphocytes.