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It should be noted that preparation of an oligosaccharide or polysaccharide usually results in a range of molecular sizes of the desired molecule.
In the preparation of molecular imprinted polymers the desired molecule (template) induces the creation of specific recognition sites in the polymer.
Then, to identify the variants with the most specific responses to the four target molecules of interest, the team engineered groups of E. coli bacteria to express green fluorescent protein (GFP) when the desired molecule was detected, thereby making the bacteria fluoresce.
But now, a team of researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University and Harvard Medical School (HMS) led by George Church, Ph.D., has developed a new method for engineering a broad range of biosensors to detect and signal virtually any desired molecule using living eukaryotic cells.
They also offer the advantage that one technique can detect a desired molecule that the others might miss.
Given their short half-life, researchers also need a way to attach them to the desired molecule before they decay.
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This initial polymer film was used for further surface functionalization by attachment of desired molecules.
Whole cell biotransformation is an upcoming tool to replace common chemical routes for functionalization and modification of desired molecules.
The formulation of the desired molecules is achieved via linear "mixing" of molecular fragments in order to match the desired performance.
While these molecules are naturally assembled through dedicated plant metabolic pathways, combinatorial biosynthesis has become an attractive tool to generate desired molecules.
Our system has greatly expanded the current microbial fatty alcohols profile that provides a new brand solution for producing complex and desired molecules in microbes.
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CEO of Professional Science Editing for Scientists @ prosciediting.com