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They were viewed as desirable alterations of the landscape.
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Many centuries of apparently desirable alterations, such as hard defences, training walls and groynes, aided by traditional dredging and disposal, are today recognised as having associated disadvantages.
Several excellent examples have been reported in which key regulatory genes underwent human selection that led to alterations of gene function or expression resulting in desirable traits [ 3, 4].
His collages are seamless alterations of record album covers.
Both may be alterations of an earlier form, "spitten image".
Preliminary lab work is underway exploring alterations of human cells to correct inherited blindness.
Would the USDA consider crops with alterations of their own DNA problematic?
There are examples showing that transgenesis may generate non-desirable phenotypic alterations as a consequence of pleiotropic changes in plant growth and development, compromising the preservation of the identity of the transformed genotype [ 5- 9].
Thirdly, PAGE provides an extremely high resolution, as desirable allelic alterations are present in heteroduplexes that form distinct bands with large distances from the bulk WT homoduplex, which enables the simultaneous identification and quantification of multiple different alterations.
Therefore, cost efficient approaches that introduce minimal alteration of the ecosystem are desirable.
This permutation strategy has the desirable property of preserving both number of alterations per gene and number of alterations per samples.
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CEO of Professional Science Editing for Scientists @ prosciediting.com