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This work aimed at designing a formulation based on nanostructured lipid carriers (NLC) for transdermal co-administration of olanzapine and simvastatin, using passive and active strategies in a combined in vitro/in vivo development approach.
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Results can be directly applied to design a formulation for a specific application.
As a starting point to design a formulation suitable for the nasal route, MDZ nasal absorption was investigated in rats.
Recently, how to design a formulation system with simultaneous diagnosis and therapy toward cancer has attracted tremendous attention.
The aim of the present investigation was to design a formulation with a considerably reduced coat weight and gum concentration for colonic delivery of 5-fluorouracil for the treatment of colorectal cancer.
The purpose of this study was to design a formulation using silicone as carrier, so that release of ivermectin (IVM) can be controlled for a long period of time.
Then, we designed a formulation to encode the problem-posing process.
In the present study we designed a formulation to use a marketed coprocessed excipient that had appropriate properties.
The materials scientist, when designing a rubber formulation, has a range of objectives and restrictions within which to operate.
The flow chart (Fig. 1) details an appropriate and meaningful method for designing a suitable formulation for the bio-mimetic DDS by theoretical calculation and evaluation.
The present data indicate the potential of designing an oil formulation of bupivacaine with a prolonged local analgetic effect exhibiting a minimum of systemic toxicity.
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