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Development of a designer strain with the ability to metabolise all hemicellulosic sugars would represent a significant breakthrough for the lignocellulosic bioethanol industry.
Genetically modified silk wasn't in vogue on fashion runways this season, but a designer strain of glow-in-the-dark silkworms suggests that such fabrics may soon be feasible.
He says that a designer strain of Streptomyces would allow researchers to combine the building blocks of various antibiotics produced by the streptomycetes and other bacteria to make novel, hybrid antibiotics.
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Assuming a sitting position on his bed, he punched numbers into a calculator and suggested some designer strains that his patient might enjoy.
Other designer strains could be used to produce vaccines, such as one against hepatitis B, and drugs, including the antimalarial artemisinin.
When I last visited, large Mason jars in the display case were filled with designer strains of weed selected by the owner, Cindy 99, whose nickname refers to a variety of designer pot.
Their methods, based on research with mouse embryonic stem cells, allow creation of so-called designer strains of mice in which virtually any gene can be disabled or knocked out.
We demonstrate the ability to rapidly construct and test close to ~1000 designer strains and identify superior performers.
The lists of essential genes and synthetic lethal gene-pairs may then be targeted to inhibit microbial growth or excluded from manipulation when constructing designer strains [ 39].
The CH999 strain of S. coelicolor, with most of the actinorhodin cluster removed, was among the first designer strains developed as a "clean" host dedicated for expression of foreign natural product clusters.
The immediate goal of future research will be to generate "designer" strains of entomopathogenic fungi that are more efficient biocontrol agents than currently used wild type strains for specific insect infestations and defined environmental conditions.
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