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The result is significant given that the 16-residue sequence of helix 3, the basis upon which compounds 3 and 4 were designed, was shown to be inactive in the fluorescence anisotropy assay (see the Supporting Information).
Crucially, the polypeptide reproducing only the 16-residue C-terminal helix 3 of HIF-1α C-TAD upon which the compound 3 was designed was shown to be inactive in this assay.
Similar(58)
In May 2013, the design was shown to be a nested, telescoping piston on an A-frame.
The animal study design was shown in Figure S3.
Schematic diagram of study design was shown in Figure 1.
The experimental design was shown in Table 1.
The evaluating design was shown in Figure 1.
A flow diagram of the study design was shown as Figure 1.
Her first 10 designs are shown at www.recoveringthecityscape.com.
The experimental design is shown in Fig. 1B.
The experimental design is shown in Fig. 2A.
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