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Prof Peter Piot, now director of the London School of Hygiene & Tropical Medicine, said: "This well designed trial in non-human primates provides the most convincing evidence to date that ZMapp may be an effective treatment of Ebola infection in humans.
As adding supraorbital leads increases surgical times and complexity, a carefully designed trial is warranted to establish the long-term benefit of this new approach.
"This well designed trial in non-human primates provides the most convincing evidence to date that ZMapp may be an effective treatment of Ebola infection in humans.
There is a need for an adequately designed trial assessing the effects of a multifaceted intervention in this age group.
Yearling crossbred steers (1,356; BW = 313.3 ± 16.0 kg) were used in a randomized complete block designed trial.
Data regarding the best antibiotherapy to use are lacking since no well designed trial to study antimicrobial treatment of VGI exists.
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Despite both theoretical and reported advantages and disadvantages between BESs and SESs, there has yet to be a well-designed trial which compares one stent design to the other.
The study, published in The Journal of the American Medical Association, is the only large and well-designed trial to compare surgery for sciatica with waiting.
A well-designed trial involves a comparison between groups formed after the randomization of patients to treatments.
The start of QUEST follows the end of another Nissen-designed trial, REVERSAL (Reversing of Coronary Atherosclerosis With Lipitor).
In a well-designed trial, Ferry et al. observed a spontaneous 28%% cure rate of symptoms in the first week, followed by 37 % after 5 7 weeks [7].
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