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Based on the presumed catalytic domains required for the synthesis of the key intermediates β-orsellinic acid and methylphloroacetophenone, two pairs of degenerate primers were designed to target specifically the β-ketoacylsynthase (KS) and C-methyltransferase (CMeT) domains of fungal non-reducing polyketide synthase (NR-PKS) genes with CMeT domains.
Three siRNA (5'-AGUGCUACAUUGCGAUACATT-3', 5'-AUGCUAAUGUCAUCAUAUCTT-3' and 5'-GGUUAUAUUGGACCUUGUATT-3'; Sigma, Belgium) were designed to target specifically Ir-LBP mRNA.
Primers were designed to target specifically GSIIE and GSIIB sequences.
Nucleotide primers were designed to target specifically an intron within the aldolase-B locus in acanthopterygian fishes.
Unlike chemotherapeutics, Ig-based therapies can be designed to target specifically tumour cells via the recognition of antigens overexpressed on their surface.
The hsa-mir-29a mimics, mimics control, hsa-mir-29a inhibitor (anti miR-95, chemicanti miR-95ed antisense oligonuchemicallydesigned to target specifically against modifiediR-29antisense inhibitoligonucleotidesdesigned and syntoesized from Ribobio (Guangzhou, China).
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Colon-specific drug delivery is designed to target drug molecules specifically to this area.
Handel-C is a programming language which is a hybrid of CSP and C, designed to target hardware implementations, specifically field-programmable gate arrays (FPGAs).
Those promotions will be printed directly on a customer's bill, and each is designed to target that customer specifically, making for a greater chance it'll become an actual conversion.
However, emerging therapies for neuroblastoma are designed to target the tumour cells specifically.
We report here the design, synthesis and biological activity of some new β-lactam derivatives specifically designed to target integrins.
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