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In the first target recognition step, the target enzyme is designed to destabilize detection probe derived from an aptamer specific to DNA polymerase containing the overhang sequence and the complementary blocker DNA, which consequently leads to the recovery of DNA polymerase activity inhibited by the detection probe.
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On Thursday, the company said that Mr. O'Brien's requests to sell its flagship paper were merely "designed to destabilize the company".
I focus much of my analysis on Anne Frances Wysocki's (2002) "A Bookling Monument" because it is explicitly designed to destabilize our reading practices.
These generally interact only transiently with the lipid bilayer, and their synthetic analogs are often designed to destabilize the membrane for drug or DNA delivery.
These operations, for which the President sought up to four hundred million dollars, were described in a Presidential Finding signed by Bush, and are designed to destabilize the country's religious leadership.
This trio of strategies, designed to destabilize and eventually topple the revolutionary government, did neither.
The prosecution framed the murders as acts of Islamic terrorism, designed to destabilize the country.
"What I have said consistently is that each time Russia takes these kinds of steps that are designed to destabilize Ukraine or violate their sovereignty that there are going to be consequences," Obama said in an interview Wednesday with CBS News.
Hendrix biographer Steven Roby mentions that Alex Constantine, writing in The Covert War Against Rock, quoted a leaked United States Senate Select Committee on Intelligence memorandum that detailed approved tactics designed to destabilize "politically attuned musicians" during the late 1960s.
However, mutations in Src that were designed to destabilize the inactive Src conformation, and therefore potentially allow Src to adopt a DFG-out conformation with a lower energetic penalty, do exhibit increased affinity for imatinib [18].
The trucks and train cars are easily moved and are designed to evade detection by inspectors.
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