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Our test was designed to be assessed in a spectrum of shoulder patients.
Although they were not designed to be assessed together, combining them allows more robust and powerful data in this setting.
To allow for early termination, the study was designed to be assessed in four equally spaced interim analyses and one final analysis.
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The simulations allowed the frequentist properties (statistical power and significance level) of candidate adaptive designs to be assessed.
It must be emphasised that this system only allows for the level of study design to be assessed, which is different to the grade of evidence.
Ultimately, new implants and new designs need to be assessed in controlled clinical studies.
In addition, it needs to be validated in a prospective study design and to be assessed for inter-rater reliability.
Any additional biases specific to individual study designs will be assessed by the reviewers and reported.
The sensitivity of the LCOE to the design is assessed statistically.
All study designs were assessed in order to broadly summarize the evidence for MHPSS.
This was designed to assess whether SCS was retained over the 8-month interval between training days.
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