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Currently available genome assemblers are not designed to assemble polyploids and the resulting assemblies are often fragmented [ 18], chimeric [ 19] and/or contain false segmental duplications [ 20].
Here, it became obvious that CAP3 is a genome assembly program not designed to assemble EST clusters containing potential splice variants: CAP3 assembly subsequently split a fraction of the clusters into separate contigs and singletons.
In this paper we describe SHRAP SHort Read Assemblyy Protocol), a sequencing protocol and assembly methodology designed to assemble a complex mammalian genome with high fidelity using short reads from such technologies.
Although whole genome assemblers are not designed to assemble metagenomic samples, they are being used for metagenomics due to the lack of assemblers capable of dealing with metagenomic samples.
Assembly parameters were stringently designed to assemble contigs representing sub-genomes within the allohexaploid genome.
However, standard assembly procedures are not designed to assemble genes from gene families, and might join reads that came from different genes.
Similar(29)
They are designed to directly assemble two parts by displacing material to form their own thread.
A chemical strategy has been purposely designed to hierarchically assemble nanoscale building blocks at the interface of solution/solid.
Here, we described a new software tool called Hapler designed to accurately assemble haplotypes from low diversity, low coverage data.
Results: We present a software package named Oases designed to heuristically assemble RNA-seq reads in the absence of a reference genome, across a broad spectrum of expression values and in presence of alternative isoforms.
Supramolecular recognition unit Bis-DeAP, 1, containing two high affinity hydrogen-bonding acceptor acceptor donor donor (AADD) arrays was designed to self-assemble into cyclic assemblies.
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