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The molar enthalpy changes (ΔrHm°) of designed pathways are negative, indicating that FFA esterification reaction is an exothermic process.
IBM has designed Pathways in Technology (P-TECH) schools, partnering with almost 100 public high schools and community colleges to create a six-year program that serves large numbers of low-income students.
To maximize the potential of microbes for biosynthetic purposes, new tools and methodologies within Metabolic Engineering are needed for the proposition and construction of de novo designed pathways.
In addition, our results can be useful for molecular design to achieve desirable fast/slow-folding hairpins, hairpins with/without specific misfolded intermediates, and hairpins that fold along designed pathways.
The consistency between the simulation of designed pathways and actual experiment results [17] proves both the reliability of the simulation platform and the validity of our pathway design.
Only pathways that can withstand the neutral bias of their host population will remain as designed; pathways that do not have adequate evolutionary 'supports' in place may either spontaneously decompose or augment, depending on the amount of ncDNA and population size.
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On the other hand, the conversion of one molecule of glycerol to lactate through the designed pathway was accompanied by the generation of one molecule of NADH.
The designed pathway has special dynamics to be functional for biological systems to work and it may show how to be enlightened by corresponding structure in nature.
The optimized transfer function was applied to a designed pathway that was evaluated by computational simulation.
The authors also succeeded in producing fluorinated triketide lactones in vivo from a fluoromalonate precursor, using a designed pathway built from a recruited ketosynthase and a modified 6-deoxyerythronolide B synthase thioesterase module.
Students may also design pathways in their own areas of interest in consultation with the director of undergraduate studies (DUS).
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