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Although small circuits can be designed manually, using the domain knowledge of the designer, this approach is not feasible for designs involving multiple pathways or even complete genomes.
Non-coding RNAs in P15 were identified by BLASTN searches using gene models from WB. Primers were designed manually according to recommendations in the Phusion HotStart II polymerase instruction manual (Tm 60°C and 22-25 bp in length) and synthesized by Sigma-Genosys.
(i) The operators considered so far were chosen by studying existing and efficient features designed manually.
A cellular automaton rule causing a specified kind of pattern was designed manually.
The emerged materials ontologies, most of which are designed manually, provide useful but relatively limited materials knowledge.
The fingerprints used in currently available cartridges were either designed manually or generated by automatically identifying and collecting features from molecule graphs.
Species-specific oligonucleotide probes (S-SONP) for canine taeniid cestodes were then designed manually based on the variable region between the conserved primers.
By taking advantage of in-line-framing, the framing members can be designed manually by using load tables published by manufacturers or spreadsheets developed in-house.
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Simulation software that employs pharmacokinetic models can be used to drive infusion pumps or to design manually controlled BET infusions.
Often, transcription factors from the same family have a very high sequence similarity, and so specific primer sets that only amplify their targets and none of the other family members may be hard to design manually.
This paper presents a passive braking device designed to manually decelerate heavy payloads with very little effort.
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