Sentence examples for designed a novel class from inspiring English sources

By employing RNA tertiary structural motifs together with the helices, we designed a novel class of self-folding RNA.

Based on the configuration and conformation of the allosteric site of GK, we have designed a novel class of amino phosphonate derivatives in order to develop potent GKAs.

With the aid of quantum chemistry calculations we have designed a novel class of tubular nanostructures obtained from the nanoscale soldering of thia-cucurbituril (thia-CB) macrocycles with transition metal ions (Hg2+, Pd2+, and Pt2+).

Based on clinical observations that treatment of acromegalic patients with a combination of somatostatin (SST) and dopamine (DA) agonists is more efficacious in controlling the disease than the use of either agent alone, we proposed and designed a novel class of chimeric SST-DA dual-agonist molecules.

To define Niclosamide's mechanism of Wnt/β-catenin inhibition, and to improve its selectivity and pharmacokinetic properties as an anticancer treatment, we designed a novel class of benzimidazole inhibitors of Wnt/β-catenin signaling based on SAR studies of the Niclosamide salicylanilide chemotype.

Interestingly, these instabilities can be utilized to design a novel class of responsive materials.

We tackle this difficulty by designing a novel class of fast regularization algorithms that relies upon differential algebra techniques.

This result suggests the possibility of designing a novel class of materials: functionally graded rubber-elastic materials (FGREMs).

In order to design a novel class of PTR1 inhibitors, we employed the thiazolidinone ring as a bioisosteric replacement for pteridine/purine ring.

A scaffold hopping approach has been exploited to design a novel class of cannabinoid (CB1) receptor antagonists for the treatment of obesity.

Our results strongly suggest that synthetic peptides such as PrP23 50 and PrP90 112 can be useful in designing a novel class of therapeutics in AD.