Previous authorisation of an orphan drug by the sponsor was associated with a 16-fold increase in the chance of authorisation compared to no previous authorisation (OR = 16.2, 95% CI = 5.5 47.4), whereas previous authorisation of other drugs and previous designation of another potential orphan drug by the sponsor yielded odds ratios (95% CI) of 11.5 (3.2–42.2) and 8.0 (2.5–25.7) respectively.
The SCAmpPs predicted cyclic products have a number of properties that are consistent with designation as potential ribosomally synthesized antimicrobial peptides, including peptide structure, amino acid composition and potential cation binding properties.
Agtmael, with a financier's boldness, eschewed the finance industry's then-common designation of "third world" to connote potential and opportunity.
The F.D.A. deemed the letter a Class 1 recall, its most serious designation, because of its potential risks, the company said.
Table 6 Estimated swelling potential of studied soils Designation Swelling potential (ε s ) Nkil Nkol Mfi Average Upper clayed layer (UCL) 2.26 1.90 2.11 2.09 Intermediate nodular layer (INL) 1.80 1.40 1.09 1.43 Bottom clayed layer (MCL) 2.11 1.75 2.50 2.12 Open image in new window Figure 7 Domains of classification of soils according to their plasticity index (in Bekkouche et al., ( 2000 )).
None of the study outcomes shall identify participants by name or exact designation to avoid potential professional or personal harm to the participants in view of opinions/ideas expressed by them.
This may be key to identifying both service and valuation potentials because land use designations (e.g., residential vs. institutional) can be indicative of potential populations and service.
Where there is a persistent under-delivery of housing, the secretary of state would have powers to direct further efforts, "including an increase in the buffer of identified land to increase the number of sites with potential for delivery; designation of a planning authority; or the creation of a New Homes Corporation".
It would be wrong to infer that the historic trend in IARC designations signals that we are approaching the end of the period of potential to discover occupational carcinogens.
MDOT determined that usage of the I-296 designation was "a potential source of confusion for motorists".
Also covered are the importance of standard cell potentials and the designation of the standard hydrogen electrode as the electrode by which all others are measured.
