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We defined an orphan drug as one designated as such in FDA's online orphan drug product designation database 16 for the proposed indication in the application.
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New patterns were submitted to CDC for assignment of a genotyping network database designation.
Nucleotide sequences for these alleles have been submitted to the CDC Streptococcus pyogenes emm sequence database (designations listed in Table 1).
Novel alleles and STs (allelic profiles) were assigned designations by the database curator following submission of DNA sequence trace chromatograms (http://www.mlst.net).net
Among the remaining 55 unclustered isolates, 39 or 8.1% belonged to preexisting SIT designations in the database, while 16 or 3.3% were not yet reported in the SITVIT2 database and represented orphan profiles.
Seven isolates (11%) of the study cohort represented distinct putative novel clones (ST1752, 1753, and 1754; additional designations from MLST database are still pending); 1 of these isolates (ST1753) was highly cephalosporin resistant.
Bush, an economist honored by the British Queen, and a prominent anti-extremism campaigner have all been secretly given a "terrorism" designation on a confidential database that banks use as a reference tool for blacklisting customers, a VICE News investigation can reveal.
We note that as more detailed information about the EYA1 gene became available, current numerical designations found in the Human Gene Mutation Database no longer match historical designations.
In 2017, the Department of Homeland Security expanded that critical infrastructure designation to include election databases and voting machines.
†SIT numbers: designations in International spoligotyping database (Spol DB4) (14 ).
The results were compared with the existing designations in the SITVIT2 database of Institute Pasteur de la Guadeloupe.
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