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"designated it with" is a correct and usable phrase in written English.
You can use it when you want to assign a value or purpose to something. For example, "The mayor designated the old building with a historical status."
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Located in an area of weak steering currents, the depression drifted to the northwest, and about six hours after first developing the cyclone intensified into a tropical storm; the National Hurricane Center designated it with the name Klaus.
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What was novel was making it a formal play, with its own name, rather than designating it with numbers like other 49ers plays.
A pair of linkage isomers are the ions [Co(NO2)(NH3)5]2+and [Co ONO)(NH3 5]2+, in which the anionic ligand is joined to the cobalt atom through nitrogen or oxygen, as shown by designating it with the formulas NO2− nitro) and ONO− nitrito), respectively.
The NHC accordingly assessed the system as developing into a tropical storm, designating it with the Greek letter Epsilon.
At 0600 UTC on July 18, the JMA upgraded the cyclone to tropical storm status, designating it with the name Koni.
Shortly after, the storm entered the area of responsibility of the Philippine Atmospheric, Geophysical and Astronomical Services Administration , immediately classifying the system as a tropical depression and designating it with the name Gilas; the JTWC later classified the system as such at 1200 UTC that day.
UNESCO designated it (along with Dry Tortugas National Park) a Biosphere Reserve in 1976 and a World Heritage site in 1979.
The idea of replacing the bridge has been around for years, but the prospects for getting it done improved significantly last month when President Obama designated it, along with a handful of other projects nationwide, for "fast track" environmental approval.
For each gene in the first geneset, we identified the strain whose Least Squares Mean value was higher and designated it as the strain with greater expression.
During the next day, the NPMOC initiated advisories on the area of disturbed weather and designated it as Tropical Cyclone 18P, with 1-minute sustained windspeeds of 55 km/h (35 mph).
They were leaders in the Al Haramain Islamic Foundation, a charity the Treasury Department closed last year after designating it a terrorist organization with links to Al Qaeda.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com