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The absence of a randomization procedure and a control group makes this design vulnerable to many forms of bias [ 36].
Information based on self-report make the study design vulnerable to possible recall bias; hence increased tendency in some individuals for whatever reason to remember both past injuries and recent symptoms.
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In most case, however, either appropriate analysis was lacking, denominators were not reported, time series data were not shown (making interrupted time series designs vulnerable to pre-existing trends), or numbers were too small to draw firm conclusions.
Prospects: Still the king in design but vulnerable to rival's ergonomics.
However, we find that the design is vulnerable when the fake data is not randomly selected.
Unfortunately for friends of massive modularity, this argument, like the argument from design, is vulnerable to a number of objections (Wilson, 2008).
However, the design is vulnerable to both Hawthorne effects and contamination.
Inevitably, this study design is vulnerable to loss to follow-up.
We used a longitudinal study design in vulnerable communities sharing livelihood strategies and agricultural production processes.
Ecological studies were also commonly used to study network characteristics at service area levels, and this design is vulnerable to the "ecological fallacy" in which associations observed between aggregate exposures and outcomes may not reflect true causal relationships at the individual level (Piantadosi et al. 1988).
However, the design is vulnerable to confounding because other factors such as diet and sunlight show temporal (e.g., seasonal) variation, which can affect the value of the biomarker as shown, for instance, for DNA damage in WBCs detected by the comet assay (Møller and Loft 2006; Møller et al. 2002).
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CEO of Professional Science Editing for Scientists @ prosciediting.com