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Our study may facilitate structure-based small molecule and antibody design to inhibit AL.
Recently, highly selective small-molecule inhibitors for CBP/p300, including SGC-CBP30 and PF-CBP1, were developed with a structure-based design to inhibit CBP BRD [101, 102].
In conclusion, this study establishes the use of multivalency in a novel HBL design to inhibit mast cell degranulation.
A novel design to inhibit anodic corrosion is proposed by separating the Al anode from the gel electrolyte when not in use, thereby effectively maintaining the available capacity of the battery.
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Gleevec was originally designed to inhibit a receptor kinase called PDGFR-beta, which is hyperactive in glioma, a brain cancer.
I suppose the routine was originally designed to inhibit boredom, and also to earn money.
It is a myriad of small businesses, unproductive subsidies, inflated state contracts and Byzantine regulations seemingly designed to inhibit productivity.
There's a ferocity in lines such as these, which he balances with a lot of orgasm impressions and sly digs about marriage ("Marriage and prison are quite similar, in that they're both institutions designed to inhibit personal freedom.
In laboratory experiments at M.I.T. and the Children's Hospital in Boston, Dr. Rupnick has shown that an entire class of compounds designed to inhibit cancer may also, without any obvious side effects, cause extraordinary weight loss.
Certainly, their clothing and fashion was more restrictive; the girdles, garters, hats, ties, and high-buttoned collars, as well as the helmet-like coiffures of women and men alike seems designed to inhibit sudden, free, and limber movement.
Perhaps this is best illustrated by the bullying behaviours most cited within academic contexts – threats to professional status and obstructive behaviours, designed to inhibit employees achieving their goals.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com