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Despite the perception that a design which uses the maximum velocity to estimate the time-of-concentration and the time-of-travel produces a conservative design, this comparison shows that this is not the case when compared to another design which uses the average wave celerity.
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In paired designs, this comparison is usually performed by using only the subjects who have collected all the necessary information, in the so-called available-case analysis.
The CAVD Vaccine Immunology Statistical Center (VISC, Seattle, WA) assisted in the design of this comparison study and provided unbiased data management and analysis to assess this objective.
Although those experiments were not designed with this comparison as a goal, this view is consistent with the suggestion that enriched husbandry practices alone may improve energy balance in such a way that putative beneficial treatment effects (e.g. due to CoQ10) are no longer apparent.
The statistical model was not prospectively designed for this comparison.
The study was designed for this comparison particularly addressing sensitivity in paucibacillary specimens such as culture-positive/smear-negative specimens and specificity in smear positive specimens with NTM.
This paper reports a set of laboratory experiments designed to test this comparison.
These percentages are surprisingly good if we consider that we have been comparing data available from two independent sets of samples analysed with two procedures, and the experiments were not originally designed to perform this comparison.
However, the study was not randomized or designed to make this comparison.
However, whether the addition octreotide to everolimus contributed to higher PFS is uncertain since the study was not randomized or designed to make this comparison.
However, the study was not designed to power this comparison and a post-hoc analysis estimates a sample size of at least 200 patients in each arm to reach statistical significance.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com