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The close relationship between statistical issues and cost is discussed, highlighting the importance of sampling design, replication and power, and comparing the costs of alternative designs through pilot studies and simulation modeling.
Whilst the principles of good experimental design (replication, randomization) are widely practised in other fields of applied science, they are not yet widely practised in hydrology (and other geophysical sciences where models are essential tools).
This Volume covers protocols for in-silico approaches to hydrocarbon microbiology, including the selection and use of appropriate statistical tools for experimental design replication, data analysis, and computer-assisted approaches to data storage, management and utilisation.
Design Replication of repeated cross sectional analysis from the original paper, using the same source (the General Household Survey) and occupation coding scheme, but extended from the period 1973-93 to 1973-2009, and including women as well as men.
Although the number of differently expressed genes that is detected in an experiment is highly sensitive to the experimental design, replication scheme, pooling of samples, and method of statistical analysis, these findings suggest that divergence in brain gene expression may be greater when individuals are separated into two very distinct behavioral classes.
We anticipate that even if the more focused Analysis 1 (closer design replication, smaller N) shows evidence of the interaction, the results of Plan 2 (which is not a replication, but has a larger N) will be those most likely to be highlighted by the authors, covered in the media, and remembered by the public.
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If the association studies have been properly designed, replication of the results in an independent population is one of the best methods to confirm an association.
11 29 On the other hand, as with any single subject research, the generalisability of n of 1 trials is enhanced with within patient (ABA or ABAB designs) replication or between patient replication.
Nevertheless, knowledge of the effect sizes of the SNPs found in a scan can be useful, for example in designing replication studies with appropriate sample sizes [ Yu et al., 2007].
To assess the ability of observational designs to replicate the results of experimental designs, researchers use design-replication studies.
In our design-replication study, we use data from a large-scale, randomized field experiment that tested the effectiveness of norm-based messages designed to induce voluntary reductions in water use.
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