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Specifically, the researchers expanded the conceptualization of the creative exploration stage to include ideation, design refinement, prototyping, and evaluation of the prototype (LaBat and Sokolowski, 1999).
During the final refinement stages alternate conformations were modeled and refined.
The creation and refinement stages are now well supported, with a significant improvement in usability.
The B-factor restraint giving the best free likelihood score is used in all refinement stages.
Second, there is a refinement stage that involves evaluating the prototype, refining the knowledge base, modifying the design and re-evaluating the improved system.
Design refinements from initial use, including changes in hydraulic loading rates and transition from single-stage to two-stage filtration, were required for long-term use of media filtration and were included in the design of the future hatchery.
Those assessments inform design refinements moving forward.
The refinement stage is a period of little organizational change.
Three design parameters of the algorithm are studied: set of STFT windows used in the rough estimation stage, width of the moving average filter and downsampling factor from the refinement stage.
"We're in the refinement stage and we're hammering ahead," he said.
The second fine stage is the refinement stage.
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