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Thus, kurtosis provides a useful guide for the design of neuronal nonlinearities.
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Due to the ability to modulate neuron survival and maturation by easy manipulation of epitope density, our design offers a versatile test bed to study the extracellular matrix (ECM) contribution in neuron development and the design of optimal neuronal scaffold biomaterials.
Design of a neuronal rescue strategy for patients receiving cisplatin will be facilitated by knowledge of the mechanism by which cisplatin causes DRG death.
Although such manipulations are commonly applied, the design and interpretation of neuronal silencing experiments present unique challenges, both technically and conceptually.
To quantitatively evaluate the performance of this approach, semi-artificial fMRI data were created from resting-state fMRI data with the following considerations: (1) an artificially designed spatial layout of neuronal activation patterns with varying overlap sizes across subjects and (2) a BOLD time series (TS) with variable parameters such as onset time, duration, and maximum BOLD levels.
Our study demonstrates that a direct role for substrate stiffness in regulating neuronal network activity and indicate that this modulation is dependent on a specific type of ECM protein, which should be taken into account for the design of biomaterials for neuronal tissue engineering.
SIGNIFICANCE Such analysis aids not only in future spike detection methods, but also in future experimental design when choosing sensors of neuronal activity.
This new information could also prove useful for researchers interested in better understanding neuronal development and might aid in the design of therapies to treat neuronal injuries or diseases, such as motor neuron disease.
The Wyler-Score is well established in the neuropathological work-up of MTS and designed on the percentage of neuronal loss within hippocampal subfields CA1 CA4.
Our results, combined with the antibacterial effect of silver nanoparticles, propose silver nanoparticles as an attractive nanomaterial with a dual activity for the design of therapeutic platforms for neuronal repair.
This study was designed to explore the role of neuronal apoptosis in the heroin-induced neurobehavioral defects of learning and memory.
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CEO of Professional Science Editing for Scientists @ prosciediting.com