The design of high-availability systems follows a number of principles derived from the concepts of modularity, fail fast, independence of failure modes, and redundancy and repair.
The macro activities consist of (i) experimental design, (ii) creation of availability and cost models, (iii) assessment, and (iv) the decision-making process.
For a more detailed description of the probe design and availability of the pan- Neisseria microarray, see Additional file 3. The PCR product probes generated were suspended in Genetix Spotting Solution for Amine slides and printed with non-adjacent replicates in triplicate onto Genetix Amine microarray slides using a Genetix QArray Mini microarray printer with 150 μm aQu solid pins.
The strengths of our study are its prospective design and availability of rich, confounder data including sociodemographic and a range of preinjury correlates.
Both the proxies and the DNS servers use anycast addressing, which offers the simplicity of design and high availability of service at the cost of partial loss of routing control.
The limitations of this study include the use of a retrospective design and the lack of availability of data regarding the circumstances of the mechanism of injury.
Additionally, it accounts for advanced European reactor design requirements, recent improvements, practical design aspects, availability of plant components and the availability of high temperature materials.
The complexity of ballast water sampling is a result of both the variety of organism diversity and behaviour, as well as ship design including availability of ballast water sampling points.
This study has a prospective design and availability of rich, confounder data including sociodemographic and a range of preinjury correlates.
The relatively large sample size, population-based study design, and availability of both genotyping and NSAID information are the strengths of the study.
