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This proposed method offered a new way to design MA and H2O2 sensors and might be easily extended to detect other nucleophilic reagents and electron acceptors based on colorimetric sensors.
Study concept and design: MA, MBS, JG.
Planning and design: MA, JMal, JMan, EW, LZ.
Concept and design: MA, OB, LD, GF; data collection and assembly: all authors; data analysis and interpretation: MA, OB, LD, GF; manuscript writing: MA, OB, GF.
MA, TB, MT and CH all contributed to the study design, MA conducted the study, supervised in the field by MT and TB.
E-CRISP, ZiFiT (Sander et al., 2010), Cas9 Design (Ma et al., 2013) and CHOPCHOP (Montague et al., 2014) utilize Bowtie (Langmead and Salzberg, 2012) to perform off-target searches allowing mismatches.
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Multi-attribute fuzzy axiomatic design (MA-FAD) is determined as a suitable research methodology for the focused problem.
The proof-of-concept of the proposed scheme is demonstrated using Berkeley static nodes and custom designed MA nodes.
Two stimulation conditions were compared in a repeated-measures design: 0.5 mA versus 1.5 mA intensity; a separate control group received no stimulation.
S. Sheng and R. W. Brodersen, Low-Power CMOS Wireless Communications: A Wideband CDMA System Design, Boston, MA: Kluwer Academic Publishers, 1998. A. P. Chandrakasan and R. W. Brodersen, Low Power Digital CMOS Design, Boston, MA: Kluwer Academic Publishers, 1995.
As an interior design destination, Ma(i sonry's offerings are eclectic in the extreme, with a vein of leathery-industrial steampunk--think welded bookcases, antique French gym equipment, surgical spotlights.
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