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As shown above, this can include drug target identification and validation, animal model selection, preclinical safety assessment, vaccine design, epidemics control and drug repositioning.
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We believe that our results are robust independently of any other epidemic types, or it can provide the methodological framework to design epidemic-specific surveillance network.
Our novel results have significant implications for understanding the dynamics of outbreaks of infectious diseases, particularly for the biological understanding of the transmission dynamics of the pathogen, estimating the severity of outbreaks, making health policy decisions, and designing epidemic control strategies.
We designed epidemic severity as a function of case-fatality rate and viral infectivity.
For example, one of Maziar's projects seeks to design an epidemic-style communication protocol for large-scale data dissemination on the Internet.
Understanding how protective behavior such as social distancing varies and the specific factors that mediate it may help with the design of epidemic control strategies.
Also, there are few previous works where a state observer is designed for epidemic models [27, 28].
Countermeasures (eg, vaccination against pneumococcal and meningococcal disease before a pandemic; mass uses of antibiotic(s) with broad spectrums of activity against common bacterial respiratory pathogens during local epidemics) designed to prevent or mitigate the effects of influenza-bacterial interactions should be major focuses of pandemic-related research, prevention, and response planning.
Design Economic and epidemic modelling study.
We consider the optimal design of controlled experimental epidemics or transmission experiments, whose purpose is to inform the practitioner about disease transmission and recovery rates.
The method controlled for long-term trend, seasonal changes, and respiratory epidemics by design.
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