On the other hand, if no known sensor system is available, one could be engineered via protein design, directed evolution, site-directed mutagenesis, or domain swapping.
"It was very intense," said David Stein, a former specialist in planning for North Carolina State, who with his wife, Achba, a former director of the university's school of landscape design, directed the students' work with the town and developer.
A seamless apparatus of projections, lighting, and sound design, directed by Ted Sperling and produced by Beth Morrison, maintained a hypnotic continuity through what might have been a disjointed collage of styles.
AFH claims to have a network of 50,000 professionals around the globe, and in their 13-year existence they've been at the forefront of a growing movement towards low-energy, low-cost but hi-tech design directed at some of the world's most pressing problems.
Though they're not part of a chain and don't have their interior design directed by a single corporate overlord, these coffee shops have a way of mimicking the same tired style, a hipster reduction obsessed with a superficial sense of history and the remnants of industrial machinery that once occupied the neighbourhoods they take over.
Overall, therefore, our results have implications for small-molecule drug design directed at multiprotein targets.
Almost all of the musicals that tour Australia come prepackaged: pre-designed, directed, orchestrated, and choreographed.
As a demonstrative example, this revised model is applied to design a de novo protein for a target backbone for which the previous model had relied on after-design directed evolution to produce a well-folded protein.
KN designed, directed and wrote and edited this paper.
CK designed, directed, and coordinated the study and drafted and finalized the manuscript.
F.M.U. was the NIH-funded Principal Investigator who designed, directed and supervised this study and wrote the initial draft of the manuscript.
