This study uses a family study design ascertaining 225 probands with substance abuse/dependence, anxiety disorders, and controls to address: (1) Is there spousal concordance or cross-concordance for substance use and/or anxiety disorders?
Heterogeneity in clinical design was ascertained by examination of the table of characteristics of included studies.
The purpose of this work is to gauge user opinions on vehicle dashboard design to ascertain the criteria important to consumers for the next generation of automobile dashboards.
Finally we recommend further observational studies with prospective design to ascertain the current findings.
(The most desirable design, prospectively ascertaining incident infections and subsequently monitoring progression, would likely be prohibitively difficult).
The observational study design cannot ascertain what proportion of the recovery rates can be accounted for by factors such as spontaneous remission over time.
We applied the nested case-control design to ascertain study subjects and two control groups from the healthy population, investigating the high-order interaction of risk factors on steatohepatitis.
To optimize study design and ascertain safety and efficacy of the chosen loading dose of 540,000 IU of cholecalciferol, we performed a pilot trial in 25 medical critically ill patients with vitamin D deficiency [ 25].
This provides the rationale for long-term prospective longitudinal studies of cohorts recruited prenatally or at birth as the optimal design to ascertain neurobehavioral deficits in relation to exposure to environmental chemicals (Krasnegor et al. 1994).
