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The performance oriented, parametric design approach we developed is structured in two parts.
Using a research by design approach, we did three rounds of observation, paper sketches, and user testing of prototypes.
Following our design approach, we provide a classification system with a runner-independent surface classification rate of more than 80%.
In order to examine the usefulness of our design approach, we have utilised two widely used evolutionary algorithms, i.e. particle swarm optimisation (PSO) and differential evolution (DE).
In both cases, stabilizing controllers are explicitly constructed by utilizing the parametric Lyapunov equation based low gain design approach we recently developed.
Using structure-based design approach, we identified 50 with improved biochemical, cell potency and reduced MW and lower lipophilicity (Log D) compared with the original hit.
Similar(29)
Manipulation of shapes, control of height of interior space, skylight setting and insulation of arena are major design approaches we can take.
Through reinvigorating the subtle structural dynamics of bound complexes and application of structure-based drug design approaches, we proposed a set of inhibitors which could be further optimized to target CRL activity.
Employing structure-based drug design approaches, we investigated the selectivity of PDE10A inhibitors against other known PDE isoforms, by methodically exploring the various sub-regions of the PDE10A ligand binding pocket.
Following an eco-design approach, we have identified the processes mostly contributing to them and we have suggested possible improvements.
It is important to note that we use this process to scaffold students' learning and practice of a design approach, but we expect as students become more adept they will adapt the process to their style and project needs -- and take on design challenges in a much more fluid and cyclical way.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com