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This scaffold was developed further in a hit-to-lead campaign to investigate other substitution vectors using a rational structure-based design approach based on X-ray crystallography data.
When limited knowledge of mean and variance of microphone mismatches is available to a designer, the robust FSBB design approach based on the worst-case mean performance (WCMP) optimization with the passband response variance (PRV) constraint is developed.
For the SCCBFs using SMA braces (SMABs), an economical and effective design approach based on the performance-based plastic design was recently derived.
244 They used a structure-based drug design approach based on the crystal structures of TTR complexed with known amyloid fibril inhibitors.
They envisioned how the masses would experience the future, relying on, in large part, a design approach based on aerodynamics known as streamlining, which was both an engineering feat and a metaphoric principle.
A systematic design approach based on applying weights to modes of failure is proposed.
A 2DOF control design approach based on an improved H ∞ linear matrix inequalities (LMI) representation is proposed.
We compare ELM with a traditional design approach based on a dataflow model.
Furthermore, a design approach based on analytical solution of partial differential equations is proposed.
For the class of linear systems a design approach based on linear programming is proposed.
Then, a design approach based on linear matrix inequalities is developed for stabilizing the subsystems.
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