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"design against" is a correct and usable phrase in written English.
It is often used in a context that suggests taking measures to prevent something or making preparations for a potential problem. For example, "The company is taking measures to design against any potential security threats."
Exact(60)
WILLIAMS: We can't design against the insidious.
The researchers tested their design against others currently available.
dieter rams tests "good design" against 10 basic measures.
Khou, C. & Pardigon, N. Identifying attenuating mutations: tools for a new vaccine design against flaviviruses.
To design against the electromigration, one needs to raise the incubation time of an interconnect beyond its service life.
Pitting corrosion is difficult to detect, predict and design against.
Design against fatigue failure in flapwise bending is considered.
His architectural shots are beautifully composed: a crenulated roofline at Uxmal suggests a woven fabric design against the sky.
Both methods require design against local and flexural buckling, and while one method also requires design against torsional buckling, the other does not.
Guidance for the design against all three buckling modes of failure is presented.
This finding may provide basic information for effective in ovo vaccines design against IBV.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com