"To whom does design address itself: to the greatest number, to the specialists or the enlightened amateur, to a privileged social class?" an interviewer once asked Charles Eames, who answered, "Design addresses itself to the need".
Considerations regarding study design address inclusion/exclusion criteria and selection of outcome measures.
"How can design address homelessness?" I ask as soon as we are in.
Here, we account for the trial design, address methodological challenges, and discuss the estimation of sample size.
Designs such as the interwoven loop design address the increased complexity of microarray experiments, which have progressed from "simple" two-group comparisons to multifactorial or time-course experiments.
The SAMS intervention and trial design address weaknesses of previous research by recruitment from a well-characterised population, definition of a feasible theory based intervention to support medication taking and careful measurement to estimate and interpret efficacy.
