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Dr. Carson decided to design a compound that would destroy abnormal white blood cells in leukemia patients through the same pathway.
The aim of this study was to design a compound transdermal patch containing diclofenac (DA) and teriflunomide (TEF) for the treatment of rheumatoid arthritis (RA).
Madras and Meltzer happened on their discovery while trying to design a compound that would bind to brain molecules called transporters, which absorb and recycle neurotransmitters like dopamine, serotonin, and norepinephrine.
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Computer-assisted (in silico) drug design is a compound design making extensive use of tools such as chemoinformatics, quantitative structure activity relationship, molecular modeling, databases, and expert systems for the prediction and simulation of drug properties and behavior.
In an area called Caochangdi Village, by the Fifth Ring Road in the city's northeast, he designed a compound for himself, some friends and a gallery called China Art Archives and Warehouse.
It is shown that the resolution of a conventional Fresnel zone plate can be improved by a factor of 10 by designing a compound zone plate with six operative orders, with the width of the outermost zone remaining unchanged.
Progen Pharmaceuticals Company (Brisbane, QLD, Australia) designed a compound called PG545.
Using indels to design effective drugs has been successfully explored by Nandan et al., [ 66] who designed a compound that targeted a 12 residue deletion in the EF-1α protein of the protozoan parasite Leishmania donovani.
Sharpe et al. have designed a compound that incorporates a "seeker" moiety similar to MPTP, but which, unlike MPTP, is not noticeably toxic to normal neural cells, and which carries a nitrogen mustard "warhead" [−N(CH2CH2Cl 2].
The microcapillary lens, formed by air bubbles in a hollow core glass capillary filled with epoxy, is a novel design of a compound refractive lens for X-rays.
Finite element analysis was used to guide the design of a compound cantilever to allow measurement of forces in any direction in the plane of the sensor.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com