Additional information of these genes is also given, including gene description, alternatively spliced transcripts/isoforms, GC content, expression data (from Unigene), Gene Ontology (GO) descriptions, pathway information and protein domain descriptions.
For each gene, general information such as gene description, pathway information, protein sequence, GO annotations, links to published literature supporting the role of this gene in apoptosis and crucial external links are provided.
Identifier search lets users input identifiers that are commonly used in public annotation databases (e.g. HGNC gene symbol, Ensembl ID, RefSeq ID, UniProt ID and other accessions) and returns links to the corresponding Gene Report page, which displays basic gene description, pathway annotation, mutations found in the COSMIC database, as well as pancreas and breast cancer expression data.
Until the 1980s, DNA repair research focused on biochemical descriptions of pathways, but now the focus is on identifying genes and linking them to proteins and phenomena.
Our descriptions of pathways and trends presented here is just the beginning of a systems biology approach to this important process.
Improved descriptions of pathways would increase the power to identify genomic regions that influence these traits.
The overall annotation of the W. somnifera transcriptome provides a valuable resource for investigating specific processes, functional descriptions and pathways.
Data were collected from individual and group interviews, observation of multidisciplinary team meetings and selected documents (eg, job descriptions, patient pathways and protocols).
Data were collected from individual and group interviews, observation of MDT meetings and selected documents (eg, job descriptions, patient pathways and protocols).
Emerging computational techniques that exploit the rich biological information captured in reaction systems require formal standardized descriptions of pathways to extract these reaction networks and avoid the alternative: time-consuming and largely manual literature-based network reconstruction.
