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The high number of HDACi consensus genes identified here gives thus a good description of the altered cellular state, which deviated from the normal endpoint of UKN1 and which is diverted in similar ways by all HDACi.
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To test this hypothesis, we first randomly permuted the base order of selected regions to preserve the base composition but to randomize all higher k-mer (k = 2,3,4,5) content ("singlet permutation"; see Methods for a description of the parameters altered in these permutation experiments).
Most of the altered eggs will die.
Since the first description of an altered RASF phenotype by Fassbender in 1983 [ 1], data have been gathered that allow us to understand the transition from an innocent mesenchymal cell to a destructive cell that plays a leading role in established RA.
This investigation is the first to attempt a comprehensive description of pathways altered by HPV16 E6 alone in transgenic mice.
Second, the visual description of the landmark is altered by noise, simulating the changes in the descriptor which may occur when the robot observes the same landmark under different scales and viewpoints.
Therefore, we have altered the description of the interaction studies to say that Slx9-1 binds at least as well as the wild-type.
We therefore altered our description of the manual invasion counts and now define blood vessel invasion by "a sudden increase in speed or visual entry of the blood vessel and disappearance out of the field of view".
One candidate transmitter that may be interacting with corazonin neurons is dopamine, based on previous descriptions of altered dopamine synthesis during stress and phenotypes associated with genetic differences in dopaminergic signaling [31] [35].
Our data alter the phenotype description of the syndrome, not only in terms of a variable degree of hyperinsulinism with possibility of conversion to diabetes in the second decade but also in the Usher-related manifestations.
You might improve "Anna Karenina" by altering the clumsiness of the description of the station master's peaked cap — a much-discussed example.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com