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Genomic characterization section in Supplementary methods (Barretina et al., 2012) provides a detailed description of sequencing data generation and variant calling pipeline.
I've modified the Materials and methods to reference exact two CCLE files from CCLE website which were used as source of TP53 mutation calls and also provided reference to genomic characterization section provided by Barretina et al., which includes detailed description of sequencing data generation and variant calling pipeline.
Similar(58)
For this purpose feline short tandem (STR) repeat markers have been investigated in several earlier studies, but no detailed description of sequence data, allelic variations or a repeat-based nomenclature is available.
The analysis of A-tract length on nucleosome positioning also provided strong evidence that oligonucleotide-length sequences rather than dinucleotides give a more accurate and complete description of sequence features that are involved in nucleosome positioning.
The interviews focused on (i) mother's recognition of signs and symptoms with which the child presented during the actual illness, (ii) mother's description of sequences of symptom presentations and of actions taken in seeking care during the child's present episode.
b The description of sequences based on Uniprot database.
Overall, SCPE outperforms JTT in the description of sequence patterns observed in structurally constrained sites.
HGVS nomenclature recommendations for description of sequence variants were used to generate DNA and protein changes for this database.
However, description of sequence variation in CN variable loci such as DEFB at 8p23 is inherently challenging.
For a parametric description of sequence annotability, a dedicated index (Ai, Annotation index) was developed in the present research and calculated for the most interesting sequence subsets.
'Minimum information about a marker gene sequence' (MIMARKS) is a recent effort developed by the Genomics Standards Consortium to implement standardization and description of sequence-based data [ 7].
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