Sentence examples for description of pathways from inspiring English sources

This investigation is the first to attempt a comprehensive description of pathways altered by HPV16 E6 alone in transgenic mice.

It has become obvious that the application of web-based and user driven software tools has great potential and benefits from the use of open and standardized formats for the description of pathways.

Along with the simple models used for univariate analyses, these supplementary data represent the second key component for constructing a biological description of pathways responsible for hypoxia adaptation using multivariate hierarchical regression models [ 28].

In order to assess the capabilities of BCML, we compared our format with the standards for the description of pathways that are most widely used by the scientific community: KGML, BioPAX and SBML (Table 1).

The commonly used node-and-edge description of pathways, where nodes represent proteins and edges the interactions between them, are useful, but do not provide structural interaction detail [ 33, 34].

Although the description of pathway assembly by the juxtaposition of three modules is a useful guide, our analysis suggests that in the case of the benzoxazinoid pathway clustering of the first two genes, Bx1 and Bx2, is the key event.

All the modules summarized in Section "Description of pathway modules" were included with a first worksheet that documented the methodology, module structure, assumptions and limitations, and a second worksheet with all the data inputs and calculations employed.

The table shows the process title (GO name), the number of gene reporters changed changed (changed), measured with the microarrays (measured) and the total number of genes present in the pathway MAPP (total) (for detailed description of pathway selection, see Methods).

Until the 1980s, DNA repair research focused on biochemical descriptions of pathways, but now the focus is on identifying genes and linking them to proteins and phenomena.

Our descriptions of pathways and trends presented here is just the beginning of a systems biology approach to this important process.

Improved descriptions of pathways would increase the power to identify genomic regions that influence these traits.