Sentence examples for described to target from inspiring English sources

Here we review the landscape of spider-venom peptides that have so far been described to target vertebrate or invertebrate NaV channels.

The inhibitory activities determined for a series of structurally related analogues support the proposed binding mode of palinurin, which is the first compound described to target this allosteric site.

In AML, the Skp2 complex has been described to target the MEF transcription factor which induces G1/S transition.

Among various compounds (from chemical, peptidic or proteic origins) described to target mitochondria, we found that only recombinant t-Bid, Bak BH3 and Bim BH3 peptides, and ABT-737 present a direct tumor-specific mitochondrio-toxicity and induce relatively large OMP due to Bax and Bak oligomerization.

Recently, miR-145 has been described to target Sox9 in chondrocytes [ 28, 29].

Moreover, RIP140 has also been described to target and repress UCP1 enhancer in brown adipocytes trough LXR binding [23].

The quantitative method described to determine target displacement cannot discriminate between patient motion, prostate motion and tissue deformation.

Optimization methods have also been described to identify targets for gene expression modification.

This method was a key success factor for finding anle138b, since it represents the first described way to target intrinsically disordered proteins.

Other oncogenic signaling molecules that are relevant for tumorigenesis have been described to be directly targeted by miR-125b.

miRNA targets were searched using a modified miRanda version v. 2.0 September 2008 [ 33], as previously described to meet plant miRNA:target pairings criteria [ 62].