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In this paper, all the polyamine derivatives previously described to present an antikinetoplastid activity are reported.
In humans, GPS are located around the reminiscent Rathke's cleft (see Figure 3), which has been described to present cilia [35], [36].
Besides, HPeV has been described to present in biannual cycles in Europe [ 9, 11, 15].
Classically, AIN has been described to present the following triad of events: fever, rash, and arthralgias [ 16- 18].
According to the composition of the known active compounds in I. indigotica, the putative synthetic pathways of these compounds are described to present the synthetic characteristics and chemical composition of I. indigotica.
On the other hand, M2 and M2-like macrophages polarize in response to IL-4 and IL-13, IL-10 or glucocorticoid hormones and are generally described to present low IL-12 and IL-6 and high IL-10 expression, as well as an increased ability to scavenge, repair and remodel tissue, promoting angiogenesis and tumour progression [ 22, 23].
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Carboxylesterases have been described to be present in several subcellular organelles.
A total of 238 proteins were identified, most of which were previously described to be present in the phloem of rice and other plants.
Nucleolin has been also described to be present in the endoplasmic reticulum [27].
The G-quadruplex was modeled on one previously described to be present within the 5' UTR of NRAS RNA and shown to mediate translational repression [23].
Like Vpx, Vpr has been described to be present in the PIC and thus might transfer the Vpx protein into the HIV-1 PIC [12], [16] [18].
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