Herein, we describe proof-of-principle studies leading to the design, synthesis and enzymatic activity of several novel, β-lactone-based, dual inhibitors of these two enzymes.
We also describe proof-of-principle studies employing light trapping in hybrid tandem solar cells, suggesting that this device architecture has the potential to achieve efficiencies well above 12%.
The manuscript describe proof-of-concept for the use of non-replicative lentiviruses to transiently deliver both DNA-specific nucleases (zinc fingers and TALENs) and donor sequences for homologous recombination-dependent gene editing.
The structure of scientific knowledge can be nicely formalized with cuts, and much of the scientific activity can be formally described as proof generation or proof transformation.
In a 2003 book, "Automated Reasoning and the Discovery of Missing and Elegant Proofs," Dr. Wos described new proofs and more elegant versions of known proofs discovered by computers.
Friends said Nemtsov had been working on a report containing what he described as proof of Russian military involvement in eastern Ukraine.
In the wide-ranging speech, the pope alluded to the recent nuclear deal with Iran (which he described as "proof of the potential of political goodwill") and reaffirmed girls' right to education.
Thomas P. Campbell, the Met director, said last month that the museum had been swayed by "facts that were not known at the time of the acquisition," evidence that Mr. Tani described as "proof that the statues were brutally stolen after 1970".
We have described a proof of concept for assessing AHCIPs.
The semantics of interacting multi-machine systems is described, and proof obligations that ensure correctness are covered.
Though he did not specifically endorse or criticize President Barack Obama's campaign against the Islamic State -- an effort he has previously described as proof the president is "always playing catch up" -- Perry held up the organization as an example of the forces Western countries must counter because of their "twisted" views.
