In this study, the authors described a time-dependent viscoelastic behaviour of stretched tissues during limb lengthening (LL).
In addition, they described a time-dependent upregulation of the osteogenic factors, osteocalcin and osteopontin, in cocultures of pOBs and OECs seeded on silk fibroin, thus indicating an on-going osteoblastic differentiation in the coculture system [ 53– 53].
When describing a time-dependent process with a linear model, we assume a constant change over the entire time, which is highly unexpected in biological processes.
These studies demonstrate that FI score development over time can be adequately described using a time dependent Poisson distribution, and that the probability of improvement, stability and worsening of the FI score is directly related to the baseline number of deficits, age, and mobility status.
Stevenson et al. [ 20] described a time- and dose-dependent increase in neutrophil chemokines, specifically CXCR2 ligands in the rat lung, which was mirrored by neutrophil infiltration.
Let the arbitrary reaction be described by a time-dependent quantity (N= ( N_{t} ) ).
In this case, the system is described by a time-dependent Hamiltonian.
When investigating a quantum system that is described by a time-dependent Hamiltonian, it is useful to introduce an invariant operator [25] as mentioned previously.
Fetal growth in the original PBPK model was described using a time-dependent fetal growth curve (Loccisano et al. 2013).
To our best knowledge, the crossing hazards phenomenon is barely investigated in genomic studies and it is usually described as a time-dependent effect of the genomic marker without any meaningful bioclinical interpretation.
Diminishing of drug effect is described by a time-dependent mono-exponential function defined by the parameter λ, which is assumed to start acting at the start of treatment and to be independent of dosing schedule and drug exposure during the trial.
