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To better describe this issue, we consider the linear problem f ( t, y, λ ) = − λ y which, as it is well known, monotonically converges to the steady-state y = 0 whenever λ > 0. The classical explicit Euler scheme, obtained with ϕ ( h, λ ) = h and F ( y n, y n − 1, …, λ ) = − λ y n − 1 does not preserve the monotonic convergence to 0 unless h is sufficiently small.
We observed that the language used to describe this issue differed between practices with high and low compliance.
Further studies focusing on hemofiltration-filter clotting are needed to better describe this issue and the different factors associated with filter clotting (such as coagulation activation or abnormalities as well as CVVH settings or catheter dysfunction).
We absolutely agree that different types of mutations would accumulate differently, and have expanded the text to describe this issue and justify our modeling of a particular class of mutation those that directly affect intracellular replication rates.
Apparently, these three samples were misinterpreted as tumors in the analysis of Rhodes et al [ 2] and Xu et al [ 3](we describe this issue further in the discussion section).
Therefore, the conclusion that a sedentary lifestyle and low cardiorespiratory fitness affects platelet function in a prothrombotic manner would probably describe this issue in an accurate way and this viewpoint is also supported from studies where the training phase was followed by a period of deconditioning.
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A Congolese adolescent girl living in Nyaragusu described this issue, explaining how "it is a challenge to ever be alone.
So far, a large number of experimental and theoretical studies describing this issue has been presented in this field.
Slikker et al. (2004a, 2004b) described this issue with the idea of dose-dependent transitions.
To the best of our knowledge, there are few if any published studies of population-based epidemiological research that have described this issue in other countries.
A high-level Ugandan respondent described this issue: "My Permanent Secretary earns less than 2 million after tax deductions yet he handles budgets of over 50 billion.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com