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WHAT THIS STUDY ADDS TO OUR KNOWLEDGE ☑ The developed placebo model could describe the data of this new population to a very good approximation, showing the strength of a population systems pharmacology approach.
At each SOA, we fitted the reciprocal function through the DLs at 1, 2, 4, and 6 intervals, and Table 3 gives the reciprocal regression equations and, as the coefficients of determination (r's) show, the reciprocal functions describe the data of Drake and Botte very well at almost all SOAs.
This is an excellent question that was also a concern of Reviewers 3 and 4. To partially address this concern, we have rewritten the Results section where we now describe the data of others who have studied the role of TC10 in the secretory pathway.
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Table 2 describes the data of all included articles [ 14, 19- 28].
Indeed, in the way we had annotated and described the data of the figure, it was incomplete and could thus be wrongly understood (see following explanation).
Bertoni et al. [10] described the data of 120 patients with POS in which dedifferentiation occurred in 24% of patients with conventional osteosarcoma.
For the COI and 28S sequences retrieved from GenBank, a GTR model with gamma-shaped variation and invariant sites best described the data of both these regions.
As previously described, the data credibility of the Hong Kong Cancer Registry has undergone substantial improvement after 1983 [ 18].
Thus, much of statistics deals with ways of describing the data and understanding relationships between pairs of variables.
Section 2 describes the data and the definition of the treatment group.
Section 3 describes the data and microeconometric methods of our analysis.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com