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Probably of Welsh descent, Map studied at the University of Paris from about 1154 to 1160.
Significantly more SNPs from GWA studies of populations of European, Asian, and African-American descent map to human orthologous regions of rat mammary cancer loci than to human orthologous regions of randomly selected rat genomic regions not known to associate with mammary cancer susceptibility.
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Homozygosity by descent mapping in a consanguineous SRP family identified a genomic region that contained DYNC2H1, a cytoplasmic dynein involved in retrograde transport in the cilium.
We combined this with the Illumina NGS platform and developed a downstream informatics pipeline to discover co-dominant (SNPs) in an F11 single-seed descent mapping population from a Golden Promise (GP) by Morex (Mx) cross.
Since more breast cancer risk polymorphisms nominated from GWA studies of populations of European descent mapped to orthologs of rat mammary cancer loci than to randomly selected regions of the rat genome, we determined if this was the case for association studies using non-European descent populations.
In a Lebanese family having five sisters with POI, Lacombe et al. (2006) established linkage to Xq21 using whole-genome SNP typing and homozygosity-by-descent mapping.
By means of Sanger sequencing of METTL23, a nonsense mutation was detected in a consanguineous ID family from Pakistan for which homozygosity-by-descent mapping had identified a region on 17q25.
Linkage analysis and identical-by-descent mapping proved that copy number variation of intron 1 of the SOX5 gene causes the pea-comb phenotype in chickens (Wright et al. 2009).
To establish if there is a quantitative difference between the niche similarity and vertical descent derived maps, we compared the nearest neighbor sets for each prokaryote.
All subsequent comparisons between the niche similarity and vertical descent derived maps were done by disregarding any pair of prokaryotes that appeared on this sequencing bias correction list.
The principal use of GERMLINE [ 27] is identity by descent (IBD) mapping between individuals, where ROH analysis is the special case of IBD within an individual.
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