Sentence examples for dermal application of from inspiring English sources
Dermal application of 0.5 g APFO for 24 h caused light skin irritation in rabbits.
Nanocarriers are highly interesting delivery systems for the dermal application of drugs.
Interestingly, no aforesaid change was observed after dermal application of SM diluted in acetone.
In the present study multiple W/O/W nanoemulsions were optimised for the dermal application of the antiviral drug aciclovir.
A study by Kennedy [99] showed a dose-dependent increase in blood concentration of organofluoro compounds in rats after dermal application of APFO.
The skin showed similar microscopic changes after dermal application of SM in all the three diluents, however; the severity of lesions was found to be time and dose dependent.
These biochemical changes were supported by the histological observations, which revealed pronounced toxic effect and damage to liver, kidney and spleen after dermal application of SM diluted in PEG-300 or DMSO.
Results of this study suggests that toxicologically significant concentrations of AMP are unlikely to be achieved in the systemic circulation and/or target tissues in humans as a result of dermal application of products containing AMP.
Dermal application of halofuginone caused a decrease in collagen content at the treated site of a cGvHD patient, and reduction in skin scores was observed in a pilot study with SSc patients.
This study focused on the preparation and characterisation of phytosphingosine (PS) containing PN (PPN) which serve as colloidal carriers for the dermal application of ceramide IIIB (CIIIB) and the stratum corneum (SC) lipids (PPNSC) such as ceramide III (CIII), cholesterol, and palmitic acid.
The design chosen was the two-stage dermal tumorigenicity assay (skin painting), with tumor initiation using a single dermal application of the carcinogen/mutagen dimethylbenz(a)anthracene applied to the back at a non-tumorigenic dose and tumor promotion by repeated dermal applications of CSC at the same site.
