So we derive B. Although the antecedent of B → C is already derived, we cannot apply this rule for the sake of consistency.
In the absence of the primary tumours, from which these metastases derived, we cannot state that this represents a reversion in the phenotypic profile, but given the widespread finding of EMT in invasive and metastatic primary tumour, it does suggest that there may be cancer cell phenotypic variability as result of the metastatic microenvironment.
As this estimate is a derived value, we cannot directly differentiate between the subsidy and co-payment.
Finally, as we also found an increased alcohol intake for the derived allele carriers, we cannot exclude the possibility that increased alcohol consumption had a survival advantage.
Although the results presented here indicate no evidence of AR CNV in DNA derived from lymphocytes, we cannot rule out CNV around the AR in DNA contained in the cells of the hair follicles themselves.
Although our data suggest that Gata3 may not be expressed in AGM-derived HSCs, we cannot rule out that Gata3 is present in some of their precursors, which has been proposed by other reports (Bertrand et al., 2005; Manaia et al., 2000).
If we assume that C/D form is derived with respect to the B form, then this would imply that they share a common ancestor that is not shared with taxon B (although it should be noted that it is equally possible that the B form is derived, in which case we cannot be sure that C and D are more closely related to one another).
However, as KGN and HeLa cells are derived from different tissues, we cannot exclude cell-type-dependent differences of SMAD heterodimerization with FOXL2.
However, they are not a statistically derived sample and thus we cannot make national estimates.
We have not performed CGH on multiple independently derived cell lines, so we cannot say whether this change is absolutely required for transformation with CCND1, PI3K-H1047R, MYC, TERT, BMI1 and sh-p53, but it seems unlikely.
Although vesicles within rab5Q79L endosomes are positive for a set of ILV marker proteins and their morphology resembles that of ILVs within multivesicular bodies derived from late endosomes, we cannot rule out that there are slight differences between those vesicles trapped within rab5Q79L endosomes and those present in multivesicular endosomes.
